Proximal heat stress up-regulates angiopoietin-1 in fingers and reduces the severity of Raynaud's phenomenon in systemic sclerosis: a single-centre pilot study.
Yoshihito ShimaAkane WatanabeNobuto InoueTetsuya MaruyamaEiji KunitomoKunihiko HamanoTakashi KawanishiMasashi TakasugiAtsushi KumanogohPublished in: Modern rheumatology (2021)
Heating the neck or elbows can alleviate RP in SSc. The heat up-regulates angiopoietin-1 in the fingers.