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The novel peroxin Pex37: the Pxmp2 family joins the peroxisomal fission machinery.

Harald W PlattaRalf Erdmann
Published in: The FEBS journal (2019)
Peroxisomes can undergo fission during cell division, followed by their segregation between mother and daughter cells. Despite species-specific variations in the molecular composition of the fission machinery, the central mechanistic factors can be assigned to two groups: the Pex11 family and the dynamin-related protein family. In a recent study, Singh et al. describe the involvement of a member of the Pxmp2-related protein family in peroxisome fission: the novel peroxin Pex37.
Keyphrases
  • induced apoptosis
  • single cell
  • cell therapy
  • stem cells
  • bone marrow
  • endoplasmic reticulum stress