Mechanical stimulation-induced purinome priming fosters osteogenic differentiation and osteointegration of mesenchymal stem cells from the bone marrow of post-menopausal women.
Catarina Bessa-AndrêsRui Pinto-CardosoKaryna TarasovaAna Luísa Pereira-GonçalvesJoana Maria Gaio-Ferreira-CastroLiliana S CarvalhoMaria Adelina CostaFátima FerreirinhaAna Canadas-SousaJosé MarinhasRolando FreitasRui LemosAdélio VilaçaAntónio OliveiraSteven N EbertJosé Bernardo Noronha-MatosPublished in: Stem cell research & therapy (2024)
Data suggest that in vitro MS restores the purinergic cell-to-cell communication fostering the osteogenic differentiation and osteointegration of BM-MSCs from Pm women, a strategy that may be used in bone regeneration and repair tactics.
Keyphrases
- bone marrow
- mesenchymal stem cells
- cell therapy
- single cell
- bone regeneration
- polycystic ovary syndrome
- umbilical cord
- stem cells
- mass spectrometry
- multiple sclerosis
- air pollution
- ms ms
- diabetic rats
- type diabetes
- oxidative stress
- electronic health record
- high glucose
- pregnant women
- adipose tissue
- cervical cancer screening
- insulin resistance
- drug induced
- breast cancer risk
- skeletal muscle
- artificial intelligence
- polycyclic aromatic hydrocarbons