Novel CFTR modulator combinations maximise rescue of G85E and N1303K in rectal organoids.
Marjolein M EnsinckLiesbeth De KeersmaeckerAnabela S RamalhoSenne CuyxStephanie Van BiervlietLieven DupontFrauke ChristZeger DebyserFrançois VermeulenMarianne S CarlonPublished in: ERJ open research (2022)
Novel combinations of CFTR modulators can further improve functional rescue of G85E and N1303K in rectal organoids, although for N1303K, more effective CFTR modulators are still needed.