Using Electronic Health Records for Personalized Dosing of Intravenous Vancomycin in Critically Ill Neonates: Model and Web-Based Interface Development Study.
Ka Ho Matthew HuiHugh S Hung San LamCheuk Hin Twinny ChowYuen Shun Janice LiPok Him Tom LeungLong Yin Brian ChanChui-Ping LeeCeleste Lom Ying EwigYin Ting CheungTeddy Tai Ning LamPublished in: JMIR medical informatics (2022)
Using EHRs, a satisfactory popPK model was verified and adopted to develop a web-based individual dose optimization interface. The interface is expected to improve treatment outcomes of IV vancomycin for severe infections among critically ill neonates. This study provides the foundation for a cohort study to demonstrate the utility of the new approach compared with previous dosing methods.