Shared Heritability of Blood Pressure and Pulse Wave Velocity: Insights From the STANISLAS Cohort.
Constance XhaardPierre de VillemereuilAthanase BenetosErwan BozecClaire Dandine-RoullandEdith Le FlochVéronique RegnaultPatrick LacolleyFaiez ZannadPatrick RossignolNicholas GirerdPublished in: Hypertension (Dallas, Tex. : 1979) (2023)
Our results suggest that the heritability of PWV is >20% and within the same range as BP heritability. It also suggests that the link between PWV and BP goes beyond phenotypic association: PWV and BP (in particular diastolic BP) share common genetic determinants. This genetic interdependence of PWV and BP appears largely polygenic.