Aerosol immunization by alginate coated mycobacterium (BCG/MIP) particles provide enhanced immune response and protective efficacy than aerosol of plain mycobacterium against M.tb. H37Rv infection in mice.

Puja S NagpalAshwani KesarwaniParul SahuPramod Upadhyay

Published in: BMC infectious diseases (2019)

These inhale-able vaccines formulation of alginate coated live mycobacterium are more immunogenic as compared to the aerosol of bacilli and they provide better protection in mice when infected with H37Rv.

Keyphrases

mycobacterium tuberculosis
immune response
high fat diet induced
water soluble
gram negative
wound healing
wild type
dendritic cells
inflammatory response