Serum neurofilament light chain concentration predicts disease worsening in multiple sclerosis.
Synne BruneEinar August HøgestølSigrid A de Rodez BenaventPål Berg-HansenMona K BeyerIngvild Sørum LeikfossSteffan D BosPiotr SowaCathrine BrunborgMagi AndorraIrene Pulido ValdeolivasSusanna AsseyerAlexander Ulrich BrandtClaudia ChienMichael ScheelKaj BlennowHenrik ZetterbergNicole Kerlero de RosboFriedemann PaulAntonio UccelliPablo VillosladaTone BergeHanne F HarboPublished in: Multiple sclerosis (Houndmills, Basingstoke, England) (2022)
Serum NfL concentration was the only factor associated with disease worsening, indicating that sNfL is a useful biomarker in MS that might be relevant in a clinical setting.