Predicting IDH mutation status in grade II gliomas using amide proton transfer-weighted (APTw) MRI.

Shanshan JiangTianyu ZouCharles G EberhartMaria A V VillalobosHye-Young HeoYi ZhangYu WangXianlong WangHao YuYongxing DuPeter C M van ZijlZhibo WenJinyuan Zhou

Published in: Magnetic resonance in medicine (2017)

IDH-wildtype lesions typically were associated with relatively high APTw signal intensities as compared with IDH-mutant lesions. The APTw signal could be a valuable imaging biomarker by which to identify IDH1 mutation status in grade II gliomas. Magn Reson Med 78:1100-1109, 2017. © 2017 International Society for Magnetic Resonance in Medicine.

Keyphrases

low grade
high grade
wild type
magnetic resonance
contrast enhanced
magnetic resonance imaging
high resolution
diffusion weighted imaging
fluorescence imaging