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Chirality Sensing of α-Hydroxyphosphonates by N-tert-Butyl Sulfinyl Squaramide.

Yao LiGuo-Hui YangCyndi Qixin HeXin LiKendall N HoukJin-Pei Cheng
Published in: Organic letters (2017)
N-tert-Butyl sulfinyl squaramides were used for chiral discrimination of α-hydroxyphosphonates using 31P NMR. A free energy relationship study indicates that both steric and the electronic effects influence the chiral recognition of the donors.
Keyphrases
  • capillary electrophoresis
  • magnetic resonance
  • ionic liquid
  • high resolution