The D1/D2-like receptor antagonist flupentixol and the D2-like receptor antagonist L-741626 decrease operant responding for nicotine and food and locomotor activity in male and female rats.
Ranjithkumar ChellianAzin Behnood-RodRyann WilsonKaren LinGrace Wing-Yan KingAdriaan W BruijnzeelPublished in: Journal of psychopharmacology (Oxford, England) (2023)
Blockade of D1/D2-like receptors with flupentixol and D2-like receptors with L-741626 decreases nicotine and food intake in rats of both sexes. These compounds also decrease locomotor activity which might be indicative of a sedative effect.
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