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Neural Net Modeling of Checkpoint Inhibitor Related Myocarditis and Steroid Response.

Filip StefanovicAndres Gomez-CamineroDavid M JacobsPoornima SubramanianIgor PuzanovMaya R ChilbertSteven G FeuersteinYan YatsynovichBenjamin SwitzerJerome J Schentag
Published in: Clinical pharmacology : advances and applications (2022)
Our study shows that a supervised learning NN can be used to model rare events such as ICI-related myocarditis and thus provide clinical insight into drivers of progression and treatment outcomes. These findings direct attention to early detection biomarkers and clinical symptoms as the best means of implementing early and potentially life-saving steroid treatment.
Keyphrases
  • dna damage
  • oxidative stress
  • depressive symptoms
  • cell proliferation