Immune Effects of Cryoablation in Woodchuck Hepatocellular Carcinoma.
Michal Mauda-HavakukNatalie M HawkenJoshua W OwenAndrew S MikhailMatthew F StarostBaktiar KarimPaul G WakimOlga L Franco-MahechaAndrew L LewisWilliam F PritchardJohn W KaranianBradford J WoodPublished in: Journal of hepatocellular carcinoma (2023)
Partial cryoablation augmented immune effects in both treated and remote untreated tumor microenvironments, as well as systemically, in woodchucks with HCC. Characterization of these mechanisms may enhance development of novel drug-device combinations for treatment of HCC.