Study on the Mechanism of Action of Different Acupuncture Regimens on Premature Ovarian Failure Model Rats.

Yonghao YuanQingchang XiaWenzhe CuiWen CaoZiyang ZhouJian PengHailiang HuangZhifei SongShuying XieRunjie GengRan LiXiaohua YuJing Zhang

Published in: Computational and mathematical methods in medicine (2022)

Acupuncture can inhibit the apoptosis of granulosa cells in ovarian tissue of rats with premature ovarian failure and improve ovarian function. The mechanism of its effect is to promote Bcl-2 gene expression and protein synthesis and inhibit Bax gene expression and protein synthesis. The conventional treatment group works best. This provides an experimental basis for the clinical use of acupuncture to intervene in the treatment of premature ovarian failure.

Keyphrases

gene expression
induced apoptosis
dna methylation
endoplasmic reticulum stress
oxidative stress
type diabetes
combination therapy
metabolic syndrome
replacement therapy