Kaposi's sarcoma in people living with HIV/aids in a public referral hospital in Peru.
Lucía Maryelena Mendoza-MoriJim Brian Valenzuela MedinaJosé Eduardo Gotuzzo HerenciaFrancisco Gerardo Bravo PuccioFernando Alonso Mejía CorderoSalim Mohanna BarrenecheaElsa Violeta González LagosPublished in: Revista peruana de medicina experimental y salud publica (2022)
Kaposi's sarcoma (KS) is the most frequent cancer in people living with HIV. Research on this condition is scarce in the region, therefore, this article aimed to describe the demographic, clinical and therapeutic characteristics of patients with HIV who developed KS at the Cayetano Heredia Hospital between 2000 and 2018. A total of 129 KS cases were identified, with a median age of 33 years, predominantly males with 92% (119/129), and mostly men who have sex with men (MSM). The median time from HIV diagnosis to KS diagnosis was five months, associated with a CD4 lymphocyte count of 64 cells/μL (IQR: 33-185) at KS diagnosis. Cutaneous involvement was the most common presentation; however, at least half also had the visceral form.
Keyphrases
- men who have sex with men
- hiv testing
- hiv positive
- hiv aids
- antiretroviral therapy
- human immunodeficiency virus
- hiv infected
- healthcare
- south africa
- adverse drug
- induced apoptosis
- primary care
- emergency department
- squamous cell carcinoma
- insulin resistance
- cell cycle arrest
- skeletal muscle
- childhood cancer
- electronic health record
- metabolic syndrome
- cell proliferation