Low Tidal Volume versus Non-Volume-Limited Strategies for Patients with Acute Respiratory Distress Syndrome. A Systematic Review and Meta-Analysis.

Allan Jay WalkeyEwan C GoligherLorenzo Del SorboCarol L HodgsonNeill K J AdhikariHannah WunschMaureen O MeadeElizabeth UlerykDean HessDaniel S TalmorB Taylor ThompsonRoy G BrowerEddy Fan

Published in: Annals of the American Thoracic Society (2018)

The trend toward lower mortality with LTV ventilation in the primary analysis and the significant relationship between the degree of tidal volume reduction and the mortality effect together suggest, but do not prove, that LTV ventilation improves mortality among critically ill adults with ARDS.

Keyphrases

acute respiratory distress syndrome
mechanical ventilation
extracorporeal membrane oxygenation
cardiovascular events
respiratory failure
risk factors
carbon dioxide
intensive care unit
type diabetes