Antidepressant treatment and mortality in people with comorbid depression and type 2 diabetes: UK electronic health record study.

Annie JefferyKate WaltersIan C K WongDavid P J Osborn Joseph F Hayes

Published in: BJPsych open (2024)

Antidepressant prescribing was highly associated with higher rates of mortality. However, we suspect that this is not a direct causal effect, but that antidepressant treatment is a marker of more severe and unsuccessfully treated depression.

Keyphrases

electronic health record
type diabetes
major depressive disorder
depressive symptoms
cardiovascular events
primary care
risk factors
cardiovascular disease
sleep quality
emergency department
clinical decision support
early onset
insulin resistance
skeletal muscle
physical activity