Association of Energy Expenditure and Efficacy in Metastatic Renal Cell Carcinoma Patients Treated with Nivolumab.
Johanna NoelAnne JouinotJérôme AlexandreGuillaume UlmannMarie BretagneZahra Castel-AjgalSixtine De PercinClémentine Vaquin-VillemineyMarie-Pierre RevelMichael PeyromaurePascaline Boudou-RouquetteJennifer ArrondeauIthar GataaJean-Philippe DurandFrançois GoldwasserOlivier HuillardPublished in: Cancers (2022)
Our study identifies an association between mRCC patients' energy expenditure and nivolumab efficacy. The measurement of REE by indirect calorimetry in routine practice could help identify patients at risk of nivolumab failure.