Primary SARS-CoV-2 infection in children and adults results in similar Fc-mediated antibody effector function patterns.
Anne T GelderloosAnke J LakerveldRutger M ScheppMioara Alina NicolaieJosine van BeekLisa BeckersRobert S van BinnendijkNynke Y RotsPuck B van KasterenPublished in: Clinical & translational immunology (2024)
In conclusion, our data provide novel insights into the development of SARS-CoV-2-specific antibody Fc-mediated effector functions in children and adults. An increased understanding of these characteristics in specific age populations is valuable for the future design of novel and improved vaccination strategies for respiratory viruses such as SARS-CoV-2.