Genetic Diversity and Acquired Drug Resistance Mutations Detected by Deep Sequencing in Virologic Failures among Antiretroviral Treatment Experienced Human Immunodeficiency Virus-1 Patients in a Pastoralist Region of Ethiopia.
Erdaw TachbeleSamuel KyobeFred Ashaba KatabaziEdgar KigoziSavannah MwesigwaMoses JolobaAlebachew MesseleWondwossen Amogne DeguMengistu LegesseRembert PieperGobena AmeniPublished in: Infection and drug resistance (2021)
The study revealed considerable prevalence of VF and ADR mutation with the associated risk indicators. Regular virological monitoring and drug resistance genotyping methods should be implemented for better ART treatment outcomes of the nation.
Keyphrases
- human immunodeficiency virus
- antiretroviral therapy
- hiv infected
- genetic diversity
- hiv infected patients
- hiv positive
- hiv aids
- hepatitis c virus
- end stage renal disease
- ejection fraction
- single cell
- newly diagnosed
- chronic kidney disease
- risk factors
- prognostic factors
- high throughput
- genome wide
- gene expression
- south africa