Viability and oxidative stress of dental pulp cells after indirect application of chemomechanical agents: An in vitro study.

Caio Luiz Lins-CandeiroLuiz Renato ParanhosNilson Ferreira de Oliveira NetoRafael Antônio Oliveira RibeiroCarlos Alberto de Souza CostaFernanda Rodrigues GuedesWashington Henrique Themoteo da SilvaAna Paula Turrioni HidalgoPaulo César de Freitas Santos Filho

Published in: International endodontic journal (2023)

The Brix3000™ enzymatic agent did not cause indirect cytotoxic effects on pulp cells, regardless of the application time. Conversely, Papacarie Duo™ reduced viability and increased ROS production by pulp cells.

Keyphrases

induced apoptosis
oxidative stress
cell cycle arrest
endoplasmic reticulum stress
cell death
nitric oxide
hydrogen peroxide
ischemia reperfusion injury
heat shock protein