Adverse events reported during weekly isoniazid-rifapentine (3HP) tuberculosis preventive treatment among people living with HIV in Uganda.
Jillian L KadotaAllan MusinguziHélène E AschmannLydia AkelloFred WelisheJane NakimuliChristopher Allen BergerNoah KiwanukaPatrick Peter John PhillipsAchilles KatambaDavid W DowdyAdithya CattamanchiFred Collins SemitalaPublished in: medRxiv : the preprint server for health sciences (2024)
In a routine setting, 3HP was safe with 16% of PLHIV reporting AEs and only 3% requiring temporary or permanent treatment interruption. These findings support 3HP expansion in routine HIV/AIDS care settings for TB prevention.