PD-L1 and Notch as novel biomarkers in Pancreatic Sarcomatoid Carcinoma: a pilot study.

Nicola SilvestrisAntonella ArgentieroOronzo BrunettiMargherita SonnessaFulvia ColonnaSabina DelcuratoloClaudio LuchiniAldo ScarpaSara LonardiFloriana NappoMatteo FassanAntonio Giovanni SolimandoLivia FucciConcetta Saponaro

Published in: Expert opinion on therapeutic targets (2021)

Our data identify a unique biological characterization of this rare pancreatic histotype. These findings provide a rationale for future studies evaluating the potential crosstalk between PD-L1/PD-1 axis and Notch pathways and prompting the development of novel therapeutics strategy.

Keyphrases

cell proliferation
electronic health record
small molecule
clinical trial
case control
human health
data analysis