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Alternatively activated macrophages promote airway inflammation through JAK3-STAT5-Fra2 in asthma.

Siyuan HuangJing WangFen LiuLiang Dong
Published in: Inflammation research : official journal of the European Histamine Research Society ... [et al.] (2022)
M2 macrophages could promote airway inflammation through JAK3-STAT5-Fra2 to induce allergic asthma. Our study offers a new insight to further understand the pathogenesis of asthma and also provides a new direction for targeted treatment.
Keyphrases
  • allergic rhinitis
  • chronic obstructive pulmonary disease
  • lung function
  • cystic fibrosis
  • air pollution
  • drug delivery
  • replacement therapy