Surface Prostatic Metaplasia, Transitional Cell Metaplasia, and Superficial Clusters of Small Basophilic Cells in the Uterine Cervix: Prevalence in Gender-Affirming Hysterectomies and Comparison to Benign Hysterectomies from Cisgender Women.
Emily R McMullen-TabryAndrew P SciallisStephanie L SkalaPublished in: Histopathology (2021)
NKX3.1 positive basal keratinocytes, transitional cell metaplasia, small basophilic cells, and surface prostatic metaplasia are all more prevalent in the cervices of individuals on gender-affirming testosterone therapy; awareness of this fact allows pathologists to avoid the overdiagnosis of dysplasia or recommendation of unnecessary follow-up procedures.
Keyphrases
- induced apoptosis
- cell cycle arrest
- single cell
- cell therapy
- mental health
- benign prostatic hyperplasia
- risk factors
- endoplasmic reticulum stress
- oxidative stress
- radical prostatectomy
- signaling pathway
- cell death
- stem cells
- metabolic syndrome
- adipose tissue
- preterm birth
- cell proliferation
- skeletal muscle
- cervical cancer screening