Integrating single-cell RNA sequencing with spatial transcriptomics reveals an immune landscape of human myometrium during labour.

Kaiyuan JiLina ChenXiaodi WangBolun WenFan YangWenfeng DengYunshan ChenGuozheng ZhangHuishu Liu

Published in: Clinical and translational medicine (2023)

Our analysis comprehensively revealed changes in immune cells, cytokines, and cytokine receptors during labour. It provided a valuable resource to detect and characterize inflammatory changes, yielding insights into the immune mechanisms underlying labour.

Keyphrases

single cell
rna seq
high throughput
endothelial cells
oxidative stress
induced pluripotent stem cells
data analysis