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Integrating single-cell RNA sequencing with spatial transcriptomics reveals an immune landscape of human myometrium during labour.

Kaiyuan JiLina ChenXiaodi WangBolun WenFan YangWenfeng DengYunshan ChenGuozheng ZhangHuishu Liu
Published in: Clinical and translational medicine (2023)
Our analysis comprehensively revealed changes in immune cells, cytokines, and cytokine receptors during labour. It provided a valuable resource to detect and characterize inflammatory changes, yielding insights into the immune mechanisms underlying labour.
Keyphrases
  • single cell
  • rna seq
  • high throughput
  • endothelial cells
  • oxidative stress
  • induced pluripotent stem cells
  • data analysis