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Decidual lymphatic endothelial cell-derived granulocyte-macrophage colony-stimulating factor induces M1 macrophage polarization via the NF-κB pathway in severe pre-eclampsia.

Yun Ji JungYeji LeeHayan KwonHyoung-Pyo KimHan-Sung KwonEunhyang ParkJoonHo LeeYoung-Han KimYong-Sun MaengJa-Young Kwon
Published in: American journal of reproductive immunology (New York, N.Y. : 1989) (2023)
In PE, dLECs expressing high levels of GM-CSF via the NF-κB-dependent pathway play a role in inducing decidual M1 macrophage polarization.
Keyphrases
  • signaling pathway
  • lps induced
  • pi k akt
  • nuclear factor
  • oxidative stress
  • adipose tissue
  • lymph node
  • endothelial cells
  • early onset
  • peripheral blood
  • cell proliferation
  • immune response
  • cerebrospinal fluid
  • nk cells