Tumour budding-based grading as independent prognostic biomarker in HPV-positive and HPV-negative head and neck cancer.
Fabian StögbauerSusanne BeckIordanis OurailidisJochen HessChristopher PorembaMaren LauterbachBarbara WollenbergAnna Maria Stefanie BuchbergerMoritz JesinghausPeter SchirmacherAlbrecht StenzingerWilko WeichertMelanie BoxbergJan BudcziesPublished in: British journal of cancer (2023)
The most comprehensive study of TB in HNSCC so far confirmed its prognostic impact in HPV-negative tumours and for the first time in HPV-positive tumours. Further studies are warranted to evaluate its applicability for therapy guidance in HNSCC.