Outcomes of Passable and Non-passable Strictures in Clinical Trials of Crohn's Disease: A Post-hoc Analysis.

Neeraj NarulaEmily C L WongParambir S DulaiJohn K MarshallJean Frederic ColombelWalter Reinisch

Published in: Journal of Crohn's & colitis (2022)

Patients with non-passable strictures can achieve symptomatic and endoscopic remission when receiving therapies used to treat CD, although they are less likely to obtain CR compared with patients without non-passable strictures. These findings support the importance of balancing the presence of non-passable strictures in trial arms.

Keyphrases

clinical trial
end stage renal disease
ejection fraction
newly diagnosed
chronic kidney disease
prognostic factors
peritoneal dialysis
phase iii
type diabetes
metabolic syndrome
systemic lupus erythematosus
skeletal muscle
insulin resistance
weight loss