AKT2 drives cancer progression and is negatively modulated by miR-124 in human lung adenocarcinoma.

Ting LiuJianjie ZhuWenwen DuWeiwei NingYang ZhangYuanyuan ZengZeyi LiuJian-An Huang

Published in: Respiratory research (2020)

Our results suggest that miR-124 overexpression can negatively regulate AKT2 and thus inhibit the progression of LUAD. Therefore, the miR-124/AKT2 axis may serve as a potential target for novel therapies for LUAD.

Keyphrases

cell proliferation
long non coding rna
signaling pathway
long noncoding rna
endothelial cells
risk assessment
squamous cell
young adults
childhood cancer