Diagnostic accuracy of three ultrasonography strategies for deep vein thrombosis of the lower extremity: A systematic review and meta-analysis.

The failure rates of single limited, serial limited, and whole-leg CUS for DVT appeared to be quite comparable. The relative failure rate of single limited CUS remains uncertain, as the DVT prevalence was lower in these studies. Therefore, this CUS strategy may only be safe in a selected group of low-risk patients. Preference for one of the strategies may be based on pretest probability assessment, feasibility, expertise, and perceived clinical relevance of isolated distal DVT.