Growth differentiation factor-11 downregulates steroidogenic acute regulatory protein expression through ALK5-mediated SMAD3 signaling pathway in human granulosa-lutein cells.

Qiongqiong JiaBoqun LiuXuan DangYanjie GuoXiaoyu HanTinglin SongJung-Chien ChengLanlan Fang

Published in: Reproductive biology and endocrinology : RB&E (2022)

This study increases the understanding of the biological function of GDF-11 and provides important insights into the regulation of ovarian steroidogenesis.

Keyphrases

induced apoptosis
signaling pathway
epithelial mesenchymal transition
endothelial cells
liver failure
cell cycle arrest
pi k akt
transcription factor
respiratory failure
drug induced
polycystic ovary syndrome
aortic dissection
adipose tissue
intensive care unit
metabolic syndrome
cell proliferation