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Prenatal maternal antidepressants, anxiety, and depression and offspring DNA methylation: epigenome-wide associations at birth and persistence into early childhood.

Beckey TrinhSabrina FaleschiniAndrea Cortes HidalgoSheryl L Rifas-ShimanAndrea A BaccarelliDawn L DeMeoAugusto A LitonjuaAlexander NeumannJanine F FelixVincent W V JaddoeHanan El MarrounHenning TiemeierEmily OkenMarie-France HivertHeather H Burris
Published in: Clinical epigenetics (2019)
The ZNF575 gene is involved in transcriptional regulation but specific functions are largely unknown. Given the widespread use of antidepressants in pregnancy, as well as the effects of exposure to anxiety and depression, implications of potential fetal epigenetic programming by these risk factors and their impacts on development merit further investigation.
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