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Evaluation of Tobramycin Exposure Predictions in Three Bayesian Forecasting Programmes Compared with Current Clinical Practice in Children and Adults with Cystic Fibrosis.

Marc BurgardIndy SandaraduraSebastiaan J van HalSonya StaceyStefanie Hennig
Published in: Clinical pharmacokinetics (2019)
On average, the predictions made by the BF programmes were similar, however substantial individual differences were observed for some patients. This suggests the need for detailed investigations of true tobramycin exposure.
Keyphrases
  • end stage renal disease
  • clinical practice
  • ejection fraction
  • newly diagnosed
  • chronic kidney disease
  • young adults
  • peritoneal dialysis
  • prognostic factors
  • patient reported outcomes