Glioblastoma (GBM) effects on quantitative MRI of contralateral normal appearing white matter.

Hatef MehrabianWilfred W LamSten MyrehaugArjun SahgalGreg J Stanisz

Published in: Journal of neuro-oncology (2018)

CEST in cNAWM of GBM patients was lower than healthy controls which could be caused by modified brain metabolism due to tumor cell infiltration. There was no difference in MT properties of the patients and controls, however, the differences in free water pool properties were mainly due to reduced T2 in cNAWM of the patients (resulting from structural changes and increased cellularity).

Keyphrases

end stage renal disease
ejection fraction
newly diagnosed
chronic kidney disease
white matter
peritoneal dialysis
magnetic resonance
single cell
cell therapy
patient reported
cerebral ischemia