A Novel Dual-Function Redox Modulator Relieves Oxidative Stress and Anti-Angiogenic Response in Placental Villus Explant Exposed to Hypoxia-Relevance for Preeclampsia Therapy.
Diana PintyeRéka Eszter SzivaMaxim MastyuginBrett C YoungSonako JacasMarianna TörökSaira SalahuddinPrakash JagtapGarry J SouthanZsuzsanna K ZsengellerPublished in: Biology (2023)
The redox modulator AKT-1005 has the potential to intervene with oxidative stress and can be efficacious for PE therapy. Future studies are underway to assess the in vivo efficacy of HMP.