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Lower systemic nitric oxide bioactivity, cerebral hypoperfusion and accelerated cognitive decline in formerly concussed retired rugby union players.

Thomas S OwensChristopher J MarleyThomas A CalverleyBenjamin S StaceyLewis FallHayato TsukamotoAngelo IannetelliTeresa FilipponiBruce DaviesGareth L JonesChristophe HirtzSylvain LehmannEdouard TuaillonNicola MarchiJacqueline K Limberg
Published in: Experimental physiology (2023)
, P = 0.021). Retired rugby union players with history of multiple concussions may be characterised by impaired molecular, cerebral haemodynamic and cognitive function compared to non-concussed, non-contact controls.
Keyphrases
  • cognitive decline
  • nitric oxide
  • mild cognitive impairment
  • subarachnoid hemorrhage
  • cerebral ischemia
  • cognitive impairment
  • brain injury
  • nitric oxide synthase
  • single molecule
  • high school