European bio-naïve spondyloarthritis patients initiating TNF inhibitor: time trends in baseline characteristics, treatment retention and response.
Sara Nysom ChristiansenLykke Midtbøll ØrnbjergSimon Horskjær RasmussenAnne Gitte LoftJohan AsklingFlorenzo IannoneJakub ZavadaBrigitte MichelsenMichael NissenFatos OnenMaria Jose SantosManuel Pombo-SuarezHeikki RelasGary John MacfarlaneMatija TomsicCatalin CodreanuBjorn GudbjornssonIrene Van der Horst-BruinsmaDaniela di GiuseppeBente GlintborgElisa GremeseKarel PavelkaEirik Klami KristianslundAdrian CiureaNurullah AkkocAnabela BarcelosCarlos Sánchez-PiedraRitva PeltomaaGareth T JonesZiga RotarRuxandra IonescuGerdur GrondalMarleen G H Van de SandeKarin LaasMikkel ØstergaardMerete Lund HetlandPublished in: Rheumatology (Oxford, England) (2022)
Our findings indicate that over the past decades, clinicians have implemented more aggressive treatment strategies in spondyloarthritis. This was illustrated by shorter disease duration at treatment initiation, decreased retention rates and higher remission rates during recent years.