High-Fat Diet Aggravates Cerebral Infarct, Hemorrhagic Transformation and Neuroinflammation in a Mouse Stroke Model.
Coline GrisottoJanice TaïléCynthia PlanesseNicolas DiotelMarie-Paule GonthierOlivier MeilhacDavid CouretPublished in: International journal of molecular sciences (2021)
Two months of HFD in adult mice were sufficient to alter the lipid profile and the control of hyperglycemia. These metabolic perturbations were significantly associated with increased infarct volume and hemorrhagic complications.
Keyphrases
- high fat diet
- cerebral ischemia
- insulin resistance
- adipose tissue
- acute myocardial infarction
- high fat diet induced
- subarachnoid hemorrhage
- atrial fibrillation
- traumatic brain injury
- lipopolysaccharide induced
- cognitive impairment
- lps induced
- brain injury
- blood brain barrier
- type diabetes
- metabolic syndrome
- heart failure
- left ventricular