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The Association Between Circulating Klotho and Dipeptidyl Peptidase-4 Activity and Inflammatory Cytokines in Elderly Patients With Alzheimer Disease.

Mohsen SedighiTourandokht Baluchnejad MojaradSoudabeh FallahNariman MoradiSiamak Afshin-MajdMehrdad Roghani
Published in: Basic and clinical neuroscience (2020)
TNF-α, IL-1β, and IL-6 are involved in AD pathophysiology, and dysregulation of DPP4 and klotho may be associated with the inflammatory response of AD. Down-regulation of miR-29a and up-regulation of miR-195 indicated the role of miRNAs in the AD process.
Keyphrases
  • inflammatory response
  • cell proliferation
  • long non coding rna
  • long noncoding rna
  • rheumatoid arthritis
  • lipopolysaccharide induced
  • middle aged
  • lps induced
  • toll like receptor
  • community dwelling