Serum klotho concentrations in older men with hypertension or type 2 diabetes during prolonged exercise in temperate and hot conditions.
Kelli E KingJames J McCormickSean R NotleyPierre BoulayNaoto FujiiTatsuro AmanoGlen P KennyPublished in: European journal of applied physiology (2023)
Given klotho's role in cytoprotection, older men with HTN and especially T2D may be at increased cellular vulnerability to prolonged exercise or physically demanding exercise in the heat.