Osteoarthritis, mobility-related comorbidities and mortality: an overview of meta-analyses.
Gustavo Constantino de CamposRaman MundiCraig WhittingtonMarie-Josée ToutounjiWilson NgaiBrendan SheehanPublished in: Therapeutic advances in musculoskeletal disease (2020)
The identified meta-analyses reported significantly increased risk of both DM and CVD (particularly, HF and IHD) among OA patients. It was not possible to confirm consistent directional or causal relationships. OA was found to be associated with increased mortality, but mostly in relation to CVD-related mortality, suggesting that further study is warranted in this area.
Keyphrases
- meta analyses
- systematic review
- cardiovascular events
- end stage renal disease
- knee osteoarthritis
- risk factors
- newly diagnosed
- ejection fraction
- chronic kidney disease
- rheumatoid arthritis
- peritoneal dialysis
- cardiovascular disease
- prognostic factors
- heart failure
- type diabetes
- patient reported outcomes
- atrial fibrillation