rhIL-7-hyFc and hIL-2/TCB2c combination promotes an immune-stimulatory tumor microenvironment that improves antitumor efficacy of checkpoint inhibitors.

Minji LeeSun-Kyoung ImSeungtae BaekMankyu JiMiyoung KimEun Ju LeeSeung Taek JiSara Ferrando-MartinezAlexandra WolfarthJun-Young LeeDaeun KimDonghoon Choi

Published in: Journal for immunotherapy of cancer (2024)

. Together, this induces an immune-stimulatory TME that improves the efficacy of checkpoint blockade.

Keyphrases

dna damage
cell cycle
oxidative stress