Analysis of Risk Factors for Tracheal Stenosis Managed during COVID-19 Pandemic: A Retrospective, Case-Control Study from Two European Referral Centre.
Giuseppe MangiameliGianluca PerroniAndrea CostantinoArmando De VirgilioLuca MalvezziGiuseppe MercanteVeronica Maria GiudiciGiorgio Maria FerraroliEmanuele VoulazCaterina GiannittoFabio AcocellaIlaria OnoratiEmmanuel MartinodUmberto CariboniPublished in: Journal of personalized medicine (2023)
Obesity, a longer time of intubation, tracheostomy, re-tracheostomy, and longer decannulation time occurred more frequently in COVID-related tracheal stenosis. These events may explain the higher number of tracheal rings involved, although we cannot exclude the direct role of SARS-CoV-2 infection in the genesis of tracheal stenosis. Further studies with in vitro/in vivo models will be helpful to better understand the role of inflammatory status caused by SARS-CoV-2 in upper airways.