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Analysis of Risk Factors for Tracheal Stenosis Managed during COVID-19 Pandemic: A Retrospective, Case-Control Study from Two European Referral Centre.

Giuseppe MangiameliGianluca PerroniAndrea CostantinoArmando De VirgilioLuca MalvezziGiuseppe MercanteVeronica Maria GiudiciGiorgio Maria FerraroliEmanuele VoulazCaterina GiannittoFabio AcocellaIlaria OnoratiEmmanuel MartinodUmberto Cariboni
Published in: Journal of personalized medicine (2023)
Obesity, a longer time of intubation, tracheostomy, re-tracheostomy, and longer decannulation time occurred more frequently in COVID-related tracheal stenosis. These events may explain the higher number of tracheal rings involved, although we cannot exclude the direct role of SARS-CoV-2 infection in the genesis of tracheal stenosis. Further studies with in vitro/in vivo models will be helpful to better understand the role of inflammatory status caused by SARS-CoV-2 in upper airways.
Keyphrases
  • sars cov
  • respiratory syndrome coronavirus
  • coronavirus disease
  • type diabetes
  • mechanical ventilation
  • metabolic syndrome
  • oxidative stress
  • cystic fibrosis
  • weight loss
  • physical activity
  • body mass index