Investigating the potential disease-modifying and neuroprotective efficacy of exercise therapy early in the disease course of multiple sclerosis: The Early Multiple Sclerosis Exercise Study (EMSES).
Morten RiemenschneiderLars Grøndahl HvidSteffen RinggaardMikkel Karl Emil NygaardSimon Fristed EskildsenTobias GaemelkeMelinda MagyariHenrik Boye JensenHelle Hvilsted NielsenMatthias KantMasoud FalahThor PetersenEgon StenagerUlrik DalgasPublished in: Multiple sclerosis (Houndmills, Basingstoke, England) (2022)
Early supervised aerobic exercise did not reduce relapse rate or global brain atrophy, but does positively affect the microstructural integrity of important motor-related tracts and nuclei.