Immunohistochemical and genetic characteristics of a colorectal mucin-rich variant of traditional serrated adenoma.

Takafumi HiromotoTakashi MurakamiYoichi AkazawaNoriko SasaharaTsuyoshi SaitoNaoto SakamotoHiroyuki MitomiAkihito NagaharaTakashi Yao

Published in: Histopathology (2018)

MR-TSAs more frequently harboured BRAF mutations than C-TSAs, and had distinct immunohistochemical characteristics. Our findings indicated that MR-TSAs could be important precursors of BRAF-mutated, microsatellite-stable subtypes of colorectal carcinoma.

Keyphrases

wild type
contrast enhanced
magnetic resonance
metastatic colorectal cancer
genome wide
gene expression