Severe antibody-mediated transfusion-related acute lung injury in an obstetric patient following transfusion of fresh frozen plasma from a non-transfused male blood donor.

Charlotte Nielsen AgergaardThure Mors HaunstrupAnne-Louise FjordsideJohn BaechRudi SteffensenKaspar René Nielsen

Published in: Clinical case reports (2021)

Transfusion-Related Acute Lung Injury (TRALI) has been associated with neutrophil reacting antibodies in transfused blood products. We report a case of life-threatening TRALI in an obstetric patient triggered by transfusion from a non-transfused male blood donor. A residual risk of TRALI exist, even in a male-only plasma setting.

Keyphrases

cardiac surgery
sickle cell disease
lipopolysaccharide induced
pregnant women
lps induced
red blood cell
case report
early onset
drug induced