Efficacy and safety of recombinant E. coli asparaginase in children with previously untreated acute lymphoblastic leukemia: A randomized multicenter study of the Dutch Childhood Oncology Group.
Inge M Van der SluisHester de Groot-KrusemanMaroeska Te LooWim J E TissingCor van den BosGertjan J L KaspersMarc BieringsWouter J W KollenThorsten KönigUwe PichlmeierHans-Jürgen KühnelRob PietersPublished in: Pediatric blood & cancer (2018)
The efficacy, safety, and immunogenicity of both asparaginase preparations are comparable. This trial was registered at www.clinicaltrials.gov as #NCT00784017; EudraCT number 2006-003180-31.