Blood concentrations of mediators released from activated neutrophils are related to the severity of alcohol-induced liver damage.

Beata Kasztelan-SzczerbinskaBartosz ZygoAnna Rycyk-BojarzynskaAgata SurdackaJacek RolinskiHalina Cichoz-Lach

Published in: PloS one (2023)

Our results point out the critical role of neutrophils in the pathogenesis of ALD. NE and MPO correlated with the intensity of inflammation, and NE was related to the severity of liver dysfunction.

Keyphrases

oxidative stress
diabetic rats
high glucose
high intensity
endothelial cells