The influence of epigenetic biological age on key complications and outcomes in aneurysmal subarachnoid haemorrhage.

Adrià Macias-GómezJoan Jiménez-BaladoIsabel Fernández-PérezAntoni Suárez-PérezMarta Vallverdú-PratsLeopoldo GuimaraensElio VivasJesus SaldañaEva Giralt-SteinhauerDaniel Guisado-AlonsoGloria VillalbaMaria-Pilar GraciaManel EstellerAna Rodriguez-CampelloJordi Jiménez-CondeAngel OisElisa Cuadrado-Godia

Published in: Journal of neurology, neurosurgery, and psychiatry (2024)

Our study indicates that B-age is independently associated with vasospasm and 12-month mortality in patients with aSAH. These findings underscore the potential role of epigenetics in understanding the pathophysiology of aSAH-related complications and outcomes.

Keyphrases

risk factors
gene expression
subarachnoid hemorrhage
cardiovascular disease
adipose tissue
metabolic syndrome
climate change
brain injury
risk assessment
blood brain barrier
cerebral ischemia